As the drug resistance of malaria parasites increases, the development of innovative and effective antimalaria drugs is of high importance. In this app note, we describe how natural products provide a vast field of new lead structures that are effective in fighting the disease.

Learn more about how CPC systems work and how they provide an automated purification solution for isolating compounds from natural product crude extracts when paired with compact chromatography systems.

Founded in 1850, The Robertet Group is a key player in the design and composition of fragrances, flavors, and natural raw materials. Working on a worldwide scale, the company generates net sales of more than 500 million euros per year. Gilson has been helping the company explore the potential of centrifugal partition chromatography (CPC) for almost six years.

In environments requiring higher throughput levels, manual pipetting methods used in sample preparation, transfer, and mixing can sometimes be time-consuming and prone to procedural errors. Consider these automated liquid handling instruments if you need to increase your sampling throughput without compromising accuracy or repeatability.

There are many variables to consider when configuring an HPLC system. To help, here are the top five questions you need to answer.

Cannabidiol (CBD) is a non-psychotropic cannabinoid from the Cannabis sativa L. (Cannabaceae) plant. Researchers have shown that CBD’s medicinal properties may be of use for treating a variety of conditions including pain, inflammation, epilepsy, and cancer.1,2 Recently, the US Food and Drug Administration (FDA) approved the first cannabis-derived drug (Epidiolex®) to treat children with rare forms of epilepsy.

Whether you’re purifying at small-scale preclinical research levels or larger manufacturing levels, Gilson’s scalable lineup of high performance liquid chromatography (HPLC) and centrifugal partition chromatography (CPC) systems has you covered. These solutions are dependable, flexible, and precise. Our team of experts is here to help you find the one that is right for you.

Preparative chromatography, a method used to separate and purify target compounds from complex mixtures, plays a crucial role in the chemical and pharmaceutical industries. In either industry, preparative chromatography has roles in the early stages of drug development, pilot studies, and process development. In this article, you'll learn how we provide support throughout this process and enable our customers and partners to achieve their purification goals from the milligrams to the kilogram scale.

When choosing a high performance liquid chromatography (HPLC) system, it's important to consider how your future needs may evolve from your current needs. In this article, you’ll learn about the advantages of modular HPLC systems when it comes to current experimental needs and how the ability to swap out HPLC components safeguards the future of your system and your research.

Liquid chromatography (LC) is the standard method used for purifying products in the discovery stages, as it is cost-effective, relatively simple to perform, and reliable. However, obtaining high purity and yield using this approach often comes at the cost of throughput, as purification runs must be lengthened to achieve greater separation between components. This article explores how users can enhance fraction collection efficiency and streamline the purification process by using the latest advances.