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Technical Notes
Centrifugal Partition Chromatography (CPC), also known as Counter Current Chromatography (CCC) is a preparative, pilot and industrial scale liquid purification technique that does not require traditional solid supports.
There are many considerations when moving from manual to automated mAb purification, and this technical note discusses some of the hardware and software considerations for maintaining sample integrity and reducing carryover when using a Gilson automated liquid handling system.
Nitrosamines are a class of semi-volatile organic chemical compounds characterized by a nitroso group attached to an amine group. In this tech note we describe a method for automating US EPA Method 521 using the Gilson ASPEC® 274 Large Volume System
This technical note shows how the use of a suitable Gilson liquid handler and TRILUTION® LH Software makes it is possible to automate post-purification analysis sample prep. Automating this process reduces manual handling errors
and provides traceability where previously there was none.
This technical note will explain different hardware configurations, as well as
software options, to use Gilson liquid handlers with TRILUTION® LH Software as autosamplers for spectrophotometric analysis.
In this technical note, we highlight how our software and products help you add extra dimensions to your fraction collection possibilities allowing you to set conditions according to specific requirements for synthetic compound purification.
Gilson provides scientists with a range of manual and automated high-precision liquid handling tools to enable CRISPR/Cas9 gene-editing research. By choosing the right tool for the right job, convenience, productivity, accuracy, and precision can all be maximized to ensure reproducible and verifiable results.
Preparative LC coupled with mass spectrometry (MS) is a well-established method for purifying target compounds. In this tech note, we demonstrate the use of a VERITY 271 LCMS system to perform mass-based purification of target peptides from a mixture. The system is controlled using TRILUTION® LC Software, which provides real-time and post-run MS and UV data.
Did you know that about 75% of known human disease genes have a recognizable match in the genome of the fruit fly? In this technical note, a lab uses the Gilson Fly Food Dispenser to dispense fly food into vials at regular intervals.
Preparative high performance liquid chromatography (HPLC) is a well-established method for purifying target compounds. Method development is usually done at a smaller scale to define sufficient resolution between the peaks without wasting large amounts of sample. It is common to scale-up the purification from a smaller column to a larger preparative one - learn more in this technical note.